BRONX, N.Y., Nov. 23, 2020 /PRNewswire-HISPANIC PR WIRE/ — Today, Montefiore Health System and Albert Einstein College of Medicine opened the doors to its new COVID-19 vaccine unit, which will enroll people in clinical trials that will test the efficacy of vaccines against the novel coronavirus. The unit is led by Barry Zingman, MD, professor of medicine at Einstein and clinical director, infectious diseases, at the Moses division of Montefiore Health System.

The vaccine unit opening comes as global coronavirus infections are rising sharply, with nearly 200,000 cases reported daily in the United States. Montefiore’s goal is to ensure more than half of all trial participants are adults most affected by COVID-19 with a focus on people older than 65. Across the country, older individuals and communities of color have been disproportionately impacted by the pandemic.

“Montefiore and Einstein have a legacy of providing inclusive access to cutting edge care,” said Andrew D. Racine, M.D., Ph.D., system senior vice president and chief medical officer at Montefiore and professor of pediatrics at Einstein. “By ensuring that historically underrepresented patients are included in COVID-19 vaccination research, this effort will help ensure the efficacy and safety of vaccines for these underrepresented patient groups.”

The new vaccine unit builds on Montefiore and Einstein’s leadership conducting COVID-19 trials and providing lifesaving clinical care to thousands of people in the community and has already started enrolling people in the AstraZeneca-Oxford vaccine AZD1222 trial. Dr. Zingman is the principal investigator at Montefiore for the vaccine, which is one of 13 COVID-19 vaccines in phase III trials and the first to be evaluated at Montefiore and Einstein. He was also the principal investigator at Montefiore and Einstein for the ACTT-1 and ACTT-2 National Institutes of Health trials, which evaluated remdesivir (now FDA-approved as a treatment for people hospitalized with COVID-19) and remdesivir plus baricitinib, respectively. 

Since March, physician-scientists at Montefiore and Einstein have studied COVID-19’s impact on almost every major health condition, ranging from asthma to cancer; examined health inequities in local communities; and helped determine which treatments work best against COVID-19.

Among its notable research, Montefiore and Einstein faculty:

–  Published the first major U.S. study on the use of steroids, which confirmed the findings of the large-scale British RECOVERY trial showing that steroids are effective in treating COVID-19; the study also revealed which patients can be harmed by steroids

–  Led the first-ever study comparing the immune responses of adults and children with COVID-19 and detected key differences that may explain why children have milder disease than adults

–  Led the development of a monoclonal antibody therapy to neutralize COVID-19—and potentially other emerging coronaviruses—clinical trials will begin in December

–  Created a blood test for detecting COVID-19 antibodies, used clinically and for research

–  Launched the first randomized, placebo-controlled, double-blind trial of convalescent plasma with NYU Langone Medicine Center, which has expanded to include the University of Miami and the University of Texas-Houston, among other locations across the country

–  Was the first New York City medical center to enroll participants in the ACTT-1 remdesivir trial and the second highest enrolling site worldwide

–  Will offer the first randomized controlled trial of dexamethasone versus baricitinib (NIAID ACTT-4 study) for the hyperinflammatory state in COVID-19

“Words cannot express my appreciation for the many people who worked so hard to establish the new COVID-19 vaccine unit, making sure underrepresented communities will have access to the most promising protection from COVID-19,” said Dr. Zingman. “To the healthcare providers and investigators who enthusiastically joined the effort and to the people who are coming in to participate in these critically important trials, we thank you for your role in helping the world end this pandemic.”

The AstraZeneca/University of Oxford vaccine is a randomized, placebo-controlled, double-blinded trial in which two people will get the vaccine for each person who receives a placebo injection. Two injections will be given during the first 29 days.

An independent analysis of the AstraZeneca-Oxford vaccine found it successfully provoked a powerful immune response against COVID-19. The study will not include people previously diagnosed with COVID-19, people whose immune systems are suppressed due to disease or medications, people with cancer, people who are pregnant or nursing, and anyone under age 18.

About Montefiore Health System
Montefiore Health System is one of New York’s premier academic health systems and is a recognized leader in providing exceptional quality and personalized, accountable care to approximately three million people in communities across the Bronx, Westchester and the Hudson Valley. It is comprised of 10 hospitals, including the Children’s Hospital at Montefiore, Burke Rehabilitation Hospital and more than 200 outpatient ambulatory care sites. The advanced clinical and translational research at its medical school, Albert Einstein College of Medicine, directly informs patient care and improves outcomes. From the Montefiore-Einstein Centers of Excellence in cancer, cardiology and vascular care, pediatrics, and transplantation, to its preeminent school-based health program, Montefiore is a fully integrated healthcare delivery system providing coordinated, comprehensive care to patients and their families. For more information please visit www.montefiore.org. Follow us on Twitter and view us on Facebook and YouTube.

About Albert Einstein College of Medicine
Albert Einstein College of Medicine is one of the nation’s premier centers for research, medical education and clinical investigation. During the 2019-20 academic year, Einstein is home to 724 M.D. students, 158 Ph.D. students, 106 students in the combined M.D./Ph.D. program, and 265 postdoctoral research fellows. The College of Medicine has more than 1,800 full-time faculty members located on the main campus and at its clinical affiliates. In 2019, Einstein received more than $178 million in awards from the National Institutes of Health (NIH). This includes the funding of major research centers at Einstein in aging, intellectual development disorders, diabetes, cancer, clinical and translational research, liver disease, and AIDS. Other areas where the College of Medicine is concentrating its efforts include developmental brain research, neuroscience, cardiac disease, and initiatives to reduce and eliminate ethnic and racial health disparities. Its partnership with Montefiore, the University Hospital and academic medical center for Einstein, advances clinical and translational research to accelerate the pace at which new discoveries become the treatments and therapies that benefit patients. Einstein runs one of the largest residency and fellowship training programs in the medical and dental professions in the United States through Montefiore and an affiliation network involving hospitals and medical centers in the Bronx, Brooklyn and on Long Island. For more information, please visit www.einstein.yu.edu, read our blog, follow us on Twitter, like us on Facebook, and view us on YouTube.

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SOURCE Montefiore Health System; Albert Einstein College of Medicine

STOCKTON, California, Nov. 20, 2020 /PRNewswire-HISPANIC PR WIRE/ — WelbeHealth, operator of four PACE programs across California, is offering a free webinar in Spanish to address coronavirus safety and manage risk for our elderly. COVID-19: What Seniors and Caregivers Need to Know, will be presented in Spanish on December 2, 2020 from 2:00pm to 3:00pm. To register call 800-734-8041 or email [email protected] and include your name and email address.  Space is limited.

Dr. Colin Robinson, MD, MPH, Medical Director for Welbe Health will be the presenter of this valuable information. Dr. Robinson will address the latest guidance on coronavirus safety and how to manage risk while staying active and engaged, as well as answer any questions about the virus, symptoms, safety, and more. The webinar will also include a Q&A session to answer questions you may have about the virus and ways to keep safe.  

During this COVID-19 global pandemic, we have all received information from various news, government and community sources on how we can stay safe. While most were helpful, some information conflicted with others creating questions for many seniors. Masks or no masks? Three feet of space or six? Stay away from all groups or just those greater than 10?

The Medical Team at WelbeHealth wants to make sure that the seniors are informed and prepared. The webinar will educate seniors and caregivers with symptoms to watch out for as well as inform on how to reduce risk of exposure to coronavirus.

Older adults and people with underlying medical conditions are at particularly high risk during the COVID-19 pandemic, underscoring the need for aggressive action to protect PACE participants. According to the National PACE Association, the average PACE participant in the U.S. is 77 years old with 8 medical conditions, many of which are chronic conditions such as diabetes, dementia, coronary artery disease, and cerebrovascular disease.

WelbeHealth operates PACE (Program of All-Inclusive Care for the Elderly), a comprehensive medical and social care model with a decades-long track record of improved quality of life, life expectancy and personal empowerment for frail seniors. Most PACE participants are able to live safely and independently in their own homes and communities rather than receive care in a nursing home. WelbeHealth operates PACE programs in San Joaquin and Stanislaus Counties – Stockton PACE; Pasadena – Pacific PACE; Long Beach – LA Coast PACE; and Fresno – WelbeHealth Sequoia PACE. 

For further information email [email protected]

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SOURCE WelbeHealth